Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia

N/ACompletedNCT01917045

Peking University First Hospital180 enrolled

Overview

The investigators noticed that Body Fat Ratio might have great influence on the efficacy of different lipid soluble anesthetics. The objective of this clinical trial was to compare the effect of that Body Fat Ratio on the efficacy of different lipid soluble anesthetics.

The objective of this clinical trial was to compare the effect of that Body Fat Ratio on the efficacy of different lipid soluble anesthetics.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

180

Conditions

Post Operative Pain Management

Interventions

Sufentanil (R30730, brand name Sufenta)DRUG

sufentanil 1ug/ml

Sufentanil (R30730, brand name Sufenta) + MorphineDRUG

sufentanil 0.5ug/ml+morphine 0.25mg/ml

MorphineDRUG

morphine 0. 5mg/ml

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * American Society of Anesthesiologists grade I-II * adults aged over 20 and below 50 years old, * non-smoker, * with normal hepatic and renal function. Exclusion Criteria: * smoker , * any kind of mental disorder or * history use of analgesics for more than 10 consecutive days, * asthma; and * those with digestion tract disorder who would get nausea or vomiting much more easily than normal people.

Outcomes

Primary Outcomes

visual analogue pain scores

we evaluate visual analogue pain scores at different time points within 24 hours after surgery

Time frame: 24hour

Secondary Outcomes

nausea & vomiting

we evaluate nausea \& vomiting at different time points within 24 hours after surgery. we ask the patient if she feel nausea or/and occured vomit, if so, 1 time will be recorded in the time point for incidence.

Time frame: 24hour

Data from ClinicalTrials.gov

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