Low-dose Spinal Morphine for Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery

Phase 4CompletedNCT01917448

Mahidol University36 enrolled

Overview

One-thirds of patients underwent video-assisted thorascopic surgery still have severe pain. Therefore we want to demonstrate weather 0.15 mg spinal morphine would reduce 24 hour postoperative requirement comparing to control group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Video-assisted Thoracoscopic Surgery

Interventions

MorphineDRUG

spinal morphine 0.15 mg

controlOTHER

Patient receive only local infiltration without spinal analgesia

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA (American Society of Anesthesiologist) physical status I to III, * Undergoing elective video-assisted thoracoscopic surgery at Siriraj and Thammasart Hospitals * capable of using a patient-controlled analgesia (PCA) machine * understanding the numeric rating scale (NRS) score for pain assessment. Exclusion Criteria: * history of allergy to the study drugs * bleeding disorder * infection of the back * refusing spinal anesthesia * history of cerebrovascular disease * using postoperative ventilator support were excluded

Locations (1)

Faculty of Medicine, Siriraj Hospital, mahidol University

Bangkok, Thailand

Outcomes

Primary Outcomes

Total post-operative morphine requirement.

Time frame: 48 hours

Secondary Outcomes

Pain after surgery

Time frame: 48 hour

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.