EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Total Abdominal Hysterectomy

Inclusion Criteria: * Females, 18-75 years of age inclusive. * American Society of Anesthesiologist (ASA) physical status 1-3. * Undergoing open total abdominal hysterectomy (i.e., laparoscopic procedures are not sufficient) without any concurrent surgical procedure(s). * Physically and mentally able to participate in the study and complete all study assessments. * Able to give fully informed consent to participate in this study after demonstrating a good understanding of the risks and benefits of the TAP. Exclusion Criteria: * Demonstrated hypersensitivity or idiosyncratic reactions to amide-type local anesthetics. * Any subject whose anatomy, or surgical procedure, in the opinion of the Investigator, might preclude the potential successful performance of a TAP. * Any subject who in the opinion of the Investigator might be harmed or be a poor candidate for participation in the study. * Any subject, who in the opinion of the Investigator, is on chronic pain medicine. * Subjects who have received any investigational drug within 30 days prior to study drug administration, or planned administration of another investigational product or procedure during their participation in this study.