Resource Use and Disease Course in Dementia (REDIC)

N/ACompletedNCT01920100

Sykehuset Innlandet HF696 enrolled

Overview

This project is based on a three-year program that aims to improve the knowledge of the socioeconomic consequences of dementia in Norway. By including patients with and without dementia in four different cohorts (from nursing homes, from memory clinics, home-dwelling persons with dementia and elderly persons without dementia), the project's aim is to describe the course of dementia, the economical cost of dementia and to look into possible risk factors for dementia.

Study Type

OBSERVATIONAL

Enrollment

696

Conditions

Neurodegenerative Diseases Dementia

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Memory clinic sample Inclusion Criteria: * All patients examined at a memory clinic with mild cognitive impairment or mild dementia Exclusion Criteria: * None In-home care sample Inclusion Criteria: * Persons 70 years of age or older receiving in-home care from the municipality Exclusion Criteria: * None Nursing-home sample Inclusion Criteria: * All persons admitted to the nursing home with an expected stay of more than four weeks. * Participants should be 65 years or older, unless established dementia disease, in which case younger persons also will be included Exclusion Criteria: * Life expectancy of less than six weeks Control sample Inclusion Criteria: * Persons 65 years or older without any sign of dementia Exclusion Criteria: * None

Locations (3)

University of Bergen

Bergen, Norway

Senter for omsorgsforskning - Midt

Namsos, Norway

Innlandet Hospital Trust

Ottestad, Norway

Outcomes

Primary Outcomes

Cost of dementia

The cost of dementia is assessed with the Resource Utilization in Dementia (RUD) (Wimo et al. 2009), for a period of three years for all the four cohorts. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Time frame: 3 years

Secondary Outcomes

The course of neuropsychiatric symptoms

The course of neuropsychiatric symptoms (depression, anxiety, psychosis, aggression, apathy, and cognition, are assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Time frame: 3 years

Quality of Life in persons admitted to nursing homes

Quality of Life is assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Time frame: 3 years

Prescription of medication

Prescription of medication is recorded at baseline, and the amount of medication used is recorded throughout the study period. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Time frame: 3 years

DNA polymorphism

DNA samples are collected for the nursing home cohort, and they are assessed for genetic polymorphism previous associated with dementia. The results are used as covariates in the analyses of the course of the symptoms and to look for risk factors for dementia.

Time frame: At baseline

Data from ClinicalTrials.gov

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