The trial will evaluate the use of the "Neurological Pupil index" NPi, measured with the digital pupillometer (NeurOptics) compared to clinical examination for better reliability. The investigators hypothesize that digital evaluation will offer a higher sensitivity/ specificity compared to clinical examination.
Absent pupillary reaction after cardiac arrest might indicate a severe hypoxic encephalopathy. Because the examination of the pupillary reaction is easy it is part of the clinical routine but due to the different medication and the dynamic process of reperfusion injury to the brain a clinical evaluation might be not precise enough. The NPi has been shown to be superior to clinical evaluation in different settings but without regard towards cardiac arrest survivors. The Pupillometer is a hand-held, cordless, and simple to use device which removes subjectivity in the measurement of pupil size and the pupillary light reflex.
Study Type
OBSERVATIONAL
Enrollment
100
Charité Universitätsmedizin Berlin
Berlin, Germany
Charité Universitätsmedizin
Berlin, Germany
Neurological Pupil index (NPi) on a scale from 0-5
NPi values by the device on a scale by 0-5; \>3 indicates normal reaction; \<3 abnormal.
Time frame: up to 7 days
Cerebral performance category (CPC)
cerebral performance category; 1-2 good outcome; 3-5 poor outcome
Time frame: Patients will be followed for the duration of hospital stay, an expected average of 2 weeks
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