The purpose of this study is to determine the potential efficacy of real-time functional magnetic resonance imaging neurofeedback (RT- functional magnetic resonance imaging (fMRI) -NF) in regulating brain activity and psychophysiological functions.
The overall goal of the outlined study is to establish a real-time functional magnetic resonance imaging neurofeedback (RT-fMRI-NF) protocol aiming at modulating brain activity and psychophysiological functions. About two weeks after the initial training session it will be estimated how stable training effects have been. The two weeks in between, subjects will receive ambulatory training of the strategies via a smartphone-based application.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
31
Subjects are provided with RT-fMRI-NF.
Subjects are provided with an ambulatory training.
Korea University
Seoul, South Korea
Blood pressure
assessed via oscillometry, expressed in mmHg
Time frame: study day 1; study day 2 (2 weeks later); anticipated: follow-up (up to 1 year)
Blood oxygenation level dependent signal of the target brain region of interest
blood oxygenation level dependent (BOLD) signal assessed via functional magnetic resonance imaging, expressed in relative BOLD signal intensity
Time frame: study day 1; study day 2 (2 weeks later); anticipated: follow-up (up to 1 year)
Feedback on adverse events during the scanner and ambulatory training
number of subjects reporting an adverse event
Time frame: study day 1; study day 2 (2 weeks later); anticipated: follow-up (up to 1 year)
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