Evaluation of a Topical Treatment for Actinic Keratosis

Inclusion Criteria: * Males or females 30 to 90 years old, inclusive, in good general health * Clinical diagnosis of Actinic Keratosis * At least 2 clinically diagnosed, 3-15 mm AK lesions on face or scalp * Patient is competent to understand and sign a consent form, and is willing and able to follow study procedures and attend all visits * Female patients of childbearing potential must have a negative urine pregnancy test prior to receiving study medication * Sexually active women of childbearing potential participating in the study must use a medically acceptable form of contraception * Pharmacologic methods of contraception should be stable for 1 month prior to Visit 1 and be maintained at same dose during the study Exclusion Criteria: * Patients who had been treated with: 5-FU, diclofenac, retinoids, ingenol mebutate or imiquimod within 4 weeks of study, immunomodulators, or interferon/interferon inducers or systemic immunosuppressants within 8 weeks of study, cryodestruction, curettage, photodynamic therapy, surgical excision on the treatment area within 4 weeks of study, systemic cancer therapy, UVA therapy, UVB therapy, laser abrasion, dermabrasion * History of hereditary angio-edema, Epilepsy or Parkinson's Disease * Erythroderma or history of immunodeficiency disorders * Pregnancy, lactation or patient who is not practicing effective contraception * History of alcohol and drug abuse within 5 years of screening * Known hypersensitivity or previous allergic reaction to any of the components of the study medication * Having a member of the same household in the trial * Patient has participated in an investigational clinical, surgical, drug or device study within the past 30 days * Patients who in the opinion of the investigator should not be included in the study for any reason, including inability to follow procedures