The purpose of this study is to evaluate the efficacy and safety of east-west collaborative treatment using bee venom acupuncture and NSAIDs on pain intensity, functional status and quality of life of patients with chronic cervicalgia
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
Bee Venom 1:20,000 under BVA Increment Protocol \- Increment Protocol as * 1st week - SC 0.2cc/day, 2 days/week * 2nd week - SC 0.4cc/day, 2 days/week * 3nd week - SC 0.8cc/day, 2 days/week
60 mg/Tab, pers os 1Tab tid, for 3 weeks
Spine Center, Kyung Hee University Hospital at Gangdong
Seoul, South Korea
Visual Analogue Scale for bothersomeness
Time frame: Changes from baseline in VAS at 1st, 2nd, 3rd, 4th and 8th week follow-up
Neck Disability Index
Time frame: Changes from baseline in NDI at 2nd, 3rd, 4th and 8th week follow-up
Depression scores on Beck's Depression Inventory
Time frame: Changes from baseline in BDI at 4th and 8th week follow-up
Quality of Life scores on EQ-5D
Time frame: Changes from baseline in EQ-5D at 2nd, 3rd, 4th and 8th week follow-up
Quality of Life scores on SF-36
Time frame: Changes from baseline in SF-36 at 4th and 8th week follow-up
Visual Analogue Scale for pain intensity
Time frame: Changes from baseline in VAS at 1st, 2nd, 3rd, 4th and 8th week follow-up
Safety profile
Any adverse events must be documented and reported.
Time frame: At every visit, up to 2 months
Credibility test
Time frame: Changes from baseline in credibility test at 4th week follow-up
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