Evaluation of Ventilatory Strategies During Laparoscopic Surgery

N/ACompletedNCT01923038

Maria Vittoria Hospital45 enrolled

Overview

Atelectasis involving declive areas often occurs during general anesthesia and may persist postoperatively. This phenomenon could be amplified by pneumoperitoneum and Trendelenburg position. Hypothesis: To evaluate whether the shape of the airway pressure-time curve, Stress Index (SI), during constant flow inflation can lead ventilator setting during general anesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Pneumonia

Interventions

First arm: patients ventilated with zero end expiratory pressurePROCEDURE

Patients ventilated with Positive End Expiratory PressurePROCEDURE

Patients ventilated with Positive End Expiratory Pressure plus Recruitment maneuverPROCEDURE

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * American Society Anesthesiology (ASA) I, II; * age \> 18 years; * elective surgery Exclusion Criteria: * ASA III, IV; * Age \< 18 years; * emergency surgery

Locations (1)

Maria Vittoria Hospital

Turin, Turin, Italy

Outcomes

Primary Outcomes

Pulmonary Stress Index

Time frame: Continuous evaluation during time of surgery. Partecipants will be followed for the duration of hospital stay, an expected average of 1 weeks

Secondary Outcomes

Cardiac Index

Time frame: Continuous evaluation during the time of surgery

Data from ClinicalTrials.gov

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