Dosing Study of Amino Acids in Seriously Ill Patients

Inclusion Criteria: * Have Stages II to IVB head and neck cancer receiving radiation and may also be receiving chemotherapy. \* Subjects are eligible for inclusion in the study regardless of primary Stages II to IVB head and neck cancer treatment modality (eg, surgery, chemotherapy). * Have voluntarily signed and dated a written informed consent form (ICF) after the nature of the study was explained to them. * Female subjects must be of non childbearing potential (defined as postmenopausal for at least 1 year or surgically sterile \[bilateral tubal ligation, bilateral oophorectomy or hysterectomy\]) or; * Female subjects of childbearing potential must be using adequate contraception (practicing 1 of the following methods of birth control): * total abstinence from sexual intercourse (minimum of 1 complete menstrual cycle before study entry), * a vasectomized partner, * contraceptives (oral, parenteral, or transdermal) for 3 consecutive months prior to study drug administration, * intrauterine device (IUD), or * double barrier method (condoms, sponge, diaphragm, or vaginal ring with spermicidal jellies or cream). * Female subjects must have a negative serum or urinary pregnancy test result at screening (serum specimen must be obtained within 14 days prior to baseline). Exclusion Criteria: * Had a loss of \> 10% of body weight within the 3 month period prior to the study as noted in the subjects medical history chart. * Have renal disease as determined by an estimated glomerular filtration rate (eGFR) \< 30 mL/min/1.73m2. * Have a hemoglobin level of \< 9 g/dl. * Have Stage 0, I, or IVC metastatic cancer. * Have diabetes. * Have any reason which, in the opinion of the Investigator, would prevent the subject from safely participating in the study. * Have, in the opinion of the Investigator, a dependence on alcohol. * Have, in the opinion of the Investigator, a dependence on illicit drugs.