Endothelial Function in Young Hispanic Adults at Risk for Type 2 Diabetes

Inclusion Criteria: * Group 1: 1. Age between 18-40 years; 2. Hispanic (we will consider a subject being Hispanic if both parents are reported as Hispanics when asked the following question: "What ethnic group do you consider that you belong to?"); 3. History of type 2 diabetes in one or both parents; 4. BMI above 27; 5. Not have participated in any exercise program for the 6 months prior to the beginning of the study. Group 2: 1. Age between 18-40 years; 2. Hispanic (same criteria as above ); 3. No history of type 2 diabetes in any first degree relative; 4. BMI under 25; 5. Not have participated in any exercise program for the 6 months prior to the beginning of the study. Exclusion Criteria: * diabetes, glucose intolerance, pregnancy, smoking, cardiovascular disease, uncontrolled hypertension, renal disease, proteinuria, cancer, infectious diseases, severe GI diseases, lung disease, electrolyte abnormalities, anemia, endocrine disorders, severe dyslipidemia, peripheral vascular disease, medications: beta-blockers, any diuretic, calcium channel blockers, ACE inhibitors, angiotensin receptor blockers, niacin, glucocorticoids, any antineoplastic agent, antibiotics, psychoactive agents, bronchodilators or insulin.