The purpose of this study is to determine whether acupuncture is effective for relieving perimenopausal symptoms.
* A randomised controlled trial with superiority design * A total of 220 participants will be included in 3 centers * 2 arms: acupuncture group and Climen® group
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
220
Acupuncture is a collection of procedures involving penetration of the skin with needles to stimulate certain points on the body. In its classical form it is a characteristic component of traditional Chinese medicine (TCM), a form of alternative medicine, and one of the oldest healing practices in the world.
Climen Tablets are commonly used for menopausal symptoms
Chengdu University of Traditional Chinese Medicine
Chengdu, Sichuan, China
First affiliated hospital of Chengdu University of TCM
Chengdu, Sichuan, China
Menopause Rating Scale
The scale was developed and validated over the years from a research network of many institutions such as Organon Germany, Infratest Munich, Universities of Muenster and Berlin,the Berlin Center for Epidemiology and Health Research, etc. It is a scale consisted of 11 items, ranging from no symptoms to very severe symptoms.
Time frame: 12 weeks after randomization
Menopausal Specific Quality of Life Questionnaire
The Menopausal Specific Quality of Life Questionnaire (MENQOL) is self-administered and consists of a total of 29 items in a Likert-scale format. Each item assesses the impact of one of four domains of menopausal symptoms, as experienced over the last month: vasomotor (items 1-3), psychosocial (items 4-10), physical (items 11-26), and sexual (items 27-29).
Time frame: asessed 0, 6, 12, 24, 36 weeks after randomization
Average hot flash score during 24 hours
Time frame: 0, 12, 24, 36 weeks after randomization
Level of Estradiol in serum
Time frame: 0, 12, 24 weeks after randomization
Level of follicle stimulating hormone in serum
Time frame: 0, 12, 24 weeks after randomization
Level of luteinizing hormone in serum
Time frame: 0, 12, 24 weeks after randomization
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