It is well accepted that during critical illness there is an increase in protein breakdown and loss of lean body mass. Previous studies have shown that during critical illness muscle breakdown increases dramatically. The aim of our study is to test the hypothesis that critically ill patients have improved outcomes with higher protein supplementation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
The study will compare different protein supplementation amounts to determine if increased protein supplementation in critically ill patients improves outcomes.
OUHSC
Oklahoma City, Oklahoma, United States
Cumulative Organ failure free days
The primary outcome will be cumulative organ failure free days (defined as no aggressive medical support for the patient's vital organ systems; including cardiovascular, respiratory, renal, bone marrow, and liver.
Time frame: 28 days
Mortality
Time frame: 28 days
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