6-week, single site, two parallel arm, randomized, controlled trial comparing the effectiveness of a High Intensity Interval Training (HIIT) versus a continuous Moderate Intensity Training (MIT) program on cardiovascular and metabolic health outcomes in overweight adolescent males. HIIT training may be a potent time-efficient strategy to induce similar metabolic and cardiovascular adaptations typically associated with MIT.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
30
UAB Physiology Lab
Birmingham, Alabama, United States
Body Composition as measured by DXA
Time frame: Baseline and 6 weeks
Body Weight
Time frame: Baseline and 6 weeks
Blood Pressure
Time frame: Baseline and 6 weeks
Body Mass Index
Time frame: Baseline and 6 weeks
Peak uptake of volume of oxygen
Time frame: Baseline and 6 weeks
Wingate Cycle test
Time frame: Baseline and 6 weeks
LDL Cholesterol
Time frame: Baseline and 6 weeks
HDL Cholesterol
Time frame: Baseline and 6 weeks
Triglycerides
Time frame: Baseline and 6 weeks
Glucose
Time frame: Baseline and 6 weeks
Insulin
Time frame: Baseline and 6 weeks
Ghrelin
Time frame: Baseline and 6 weeks
Leptin
Time frame: Baseline and 6 weeks
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Adiponectin
Time frame: Baseline and 6 weeks
PYY
Time frame: Baseline and 6 weeks
IL-6
Time frame: Baseline and 6 weeks
TNF-alpha
Time frame: Baseline and 6 weeks
Total antioxidant capacity
Time frame: Baseline and 6 weeks
Protein Carbonyls
ELISA assay purchased from NW LifeSciences. Prior to analysis, all serum samples were assayed for protein concentration based on the methods of Bradford and adjusted to 4 mg・mL-1 protein using a phosphate buffer. Protein carbonyls, a measure of protein oxidation, were analyzed in duplicate in 50 μl of sera using a commercially available ELISA kit (NWK-PCK01).The intra- and interassay coefficients of variation were 2.7 % and 5%. The lower detection limit of the assay was 0.1 nmol/mg.
Time frame: Baseline and 6 weeks
Free living energy expenditure as measured by accelerometer
Time frame: Baseline and 6 weeks
Appetite/satiety measures
composite score
Time frame: baseline & 6 weeks
Quality & satisfaction with life
composite score
Time frame: baseline & 6 weeks
Rate of perceived exertion during exercise via Borg Scale
Time frame: baseline and 6 weeks
24-hour dietary recall
Time frame: pre-baseline, baseline, 6 weeks
Self Motivation Inventory
Time frame: baseline and 6 weeks
Profile of Mood States
Time frame: baseline & 6 weeks