Comparative Study of the Bioavailability of Magnesium Administrated by Two ChronoMag Smart Tablet® 50 mg Versus Three Mag2® Tablets 100mg.

Inclusion Criteria: * Healthy male volunteers * Patient aged between 18 and 50 * Patient with a normal blood magnesium rate between 0.65 and 1.05 mmol/l * Patient with vital signs values considered as normal by the investigator before drug administration * Sufficient cooperation and understanding to comply with the requirements of study. * Patient without medication during the 7 days preceding the inclusion * Acceptance to give a written consent. * Affiliation at system of French social security. * Inscription or acceptation of inscription at national register of voluntaries participant at research. Exclusion Criteria: * Against magnesium-indication: hypersensitivity known at carbonate or magnesium chloride or at one of the excipients. * Patient with medication or supplementation of magnesium * Severe renal insufficiency with a creatine clearance ≤ 30ml/min * Medical and chirurgical history considered as incompatible with the study * A progressive pathology during the inclusion * A consumption of more than 50g of dark chocolate per day * An excessive alcohol consumption, an excessive tobacco consumption ( more than 10 cigarettes a day), an excessive tea, coffee or drink with caffeine consumption or drug addictions * Patient who participated in another clinical trial located in exclusion period or received benefits \> 4500 euros during 12 months before the beginning of trial. * Patient with cooperation and understanding insufficiency to comply with the requirements of protocol * Minor or patient with social protection (curatorship, tutorship…) * No affiliation at system of French social security