Effects of Intensive Statin Treatment on Left Ventricular Function

Inclusion Criteria: 1. ≥ 18 years of age 2. the first time clinical diagnosis of acute anterior myocardial infarction , the time of onset ≤ 12 hours ,intends underwent emergency PCI 3. informed consent Exclusion Criteria: 1. Taking , or the need for long-term use of statins is greater than the initial dose 2. treated with PCI again within a mouth 3. active liver disease or liver dysfunction 4. the diagnosis of myopathy 5. severe renal insufficiency ( serum creatinine \> 178umol / L ) 6. Statin drug allergy or had a serious adverse reaction 7. severe aortic stenosis or mitral stenosis , hypertrophic obstructive cardiomyopathy , pericardial disease 8. pregnancy 9. malignancy or any other end-stage diseases result in a life expectancy of \< 6 months 10. be participating in other clinical studies 11. not suitable for inclusion of the other cases 12. not treated with PCI