Single Center Experience Over a Decade in Living Donor Liver Transplantation for Egyptian Patients With Hepatocellular Carcinoma: Stretching the Limits

Inclusion Criteria: * Egyptien Patients with HCC * Patients within Milan Criteria * Patients beyond Milan criteria are selected on a case by case basis until 2005. From 2005 , patients beyond Milan criteria are subjected to down staging protocol and then reassessed (pre transplantation local ablative therapy either with RFA or TACE according to the size and the site of the lesion and we wait for 12 weeks after ablation ,only those with well ablated lesions, decreased AFP and no denovo lesions were transplanted). Exclusion Criteria: * • Evidence of macro vascular invasion by CT portography and/or US duplex. * Metastatic HCC * General contraindications for LT (ongoing sepsis, other major co morbidities,…). * Early postoperative mortality (first1 month). * Post transplant mortality during the period of follow up due to any cause other than recurrent HCC (e.g. sepsis, rejection, cardiological or cerebrovascular complications…)