LDH as a Biochemical Biomarker to Predict Organ Failure in the Emergency Department Setting

N/ACompletedNCT01937676

Karolinska Institutet1,250 enrolled

Overview

The purpose of this study is evaluate if K3, a novel biomarker, sampled at arrival to the emergency department can be used to predict the development of organ failure measured as SOFA score. K3 consists of lactate dehydrogenase, albumin and magnesium combined.

Study Type

OBSERVATIONAL

Enrollment

1,250

Conditions

Multiple Organ Failure

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥18 years * Admitted to emergency department, Karlstad Central Hospital, Sweden Exclusion Criteria: * Not in need of venous blood sample

Locations (1)

Karlstad Central Hospital

Karlstad, Sweden

Outcomes

Primary Outcomes

Development of multiple organ failure

Measured as SOFA score.

Time frame: 30 days or complete ICU stay

Secondary Outcomes

Cardiac function

Is it possible to predict cardiac function with the novel biomarker K3, which consists of lactate dehydrogenase, albumin, and magnesium combined?

Time frame: 30 days or complete ICU stay

All cause mortality

Time frame: 30 days after admission to emergency department

Data from ClinicalTrials.gov

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