Enhanced Recovery After Surgery (ERAS) programs have been introduced with purposes of reducing the surgical stress response and obtaining optimal recovery after surgery.
There is strong evidence of the usefulness of the ERAS programs in patients undergoing colorectal surgery in terms of significantly reduced postoperative complications and shorter length of hospital stay, compared to the patients of conventional treatment. However, few studies exist about the implication of ERAS programs in the laparoscopic gastrectomy. The aim of this study was to compare the recovery rate, morbidity, and quality of life in the patients undergoing laparoscopic gastrectomy for gastric cancer, receiving either ERAS protocol or conventional postoperative cares.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
1. Patient's preoperative counseling \& education before surgery 2. No Bowel preparation 3. Oral Carbohydrate Solution (OCS) loading until 2hours before surgery 4. Fluid restriction \& Management by pulse contour analysis or transesophageal doppler 5. Early mobilization 6. Early oral feeding (postoperative 1 day - sips of water, 2 days - semifluid diet (SFD), 3 days - soft blended diet (SBD)) 7. Epidural patient controlled analgesics (no opioids analgesics) 8. Postoperative Nausea Active Control 9. Thromboembolism prophylaxis by low molecular weighted heparin (LMWH) 10. Perioperative High content Oxygen therapy 11. No drain insertion 12. No Levin tube 13. Patients will be discharged at POD#4 if there's no problem.
1. No Patient's preoperative counseling \& education before surgery 2. Bowel preparation 3. No Oral Carbohydrate Solution (OCS) loading until 2hours before surgery 4. Conventional Fluid Management by clinical signs (Urine output, heart rate etc.) 5. Conventional Mobilization 6. Conventional oral feeding (POD#2 SOW, #3 SFD, #4 SBD) 7. IV PCA 8. Postoperative Nausea Control if needed 9. No Thromboembolism prophylaxis 10. No or Low Content Oxygen therapy 11. Routine drain insertion 12. Levin tube insertion if needed
Seoul National University Bundang Hospital
Seongnam, Geynggi, South Korea
Recovering Rate
1. Tolerance of diet for 24 hours A. Able to eat one third of more of soft-blend meal without abdominal discomfort, bloating, nausea, or vomiting 2. Analgesic-free (oral or IV analgesic drugs not necessary after cessation of PCA) 3. Safe ambulation (ambulation of 600m without assistance) 4. Afebrile status without major complications (fever defined as body temperature greater than 37.5) * Above total 4 criteria should be satisfied for the evaluation of complete recovery.
Time frame: 4 days after surgery
Postoperative length of hospital stay
Time frame: up to 4 weeks after surgery
Time to tolerance of a full diet
Time frame: up to 1 month after surgery
Time to first bowel motion Time to first bowel motion
Time frame: up to 7 days after surgery
Complications during the admissionTime to first bowel motion
Time frame: up to 30 days after surgery
Readmission rate
Time frame: up to 30 days after surgery
Pain scores based on a visual analog scale the day of surgery and the subsequent 3 days
postoperative 2hours, 6 hours, 1 days, 2 days, 3 days
Time frame: up to 3 days after surgery
Quality of life
European organization for research and treatment of cancer (EORTC) and gastrointestinal quality of life index (GIQLI) questionnaire on postoperative 5 days, 1 month
Time frame: up to 1 month after surgery
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