Prospective Study : Helicobacter Pylori Eradication Therapy in Accordance With Past Antibiotics Use

Phase 4UnknownNCT01938534

Ajou University School of Medicine440 enrolled

Overview

Prospective study : Helicobacter pylori eradication therapy in accordance with past antibiotics use.

Antibiotics resistant is serious problem in helicobacter pylori eradication. Clarithromycin is very important antibiotics in eradication. But clarithromycin resistance is increased. Major cause of clarithromycin resistance is past consumption of macrolide. Thus the investigators propose eradication of macrolide used group bismuth contained four drugs therapy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

440

Conditions

Helicobacter Eradication

Interventions

Helicobacter pylori eradicationDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Peptic ulcer disease * Gastric MALT lymphoma * Early gastric cancer * Familial history of gastric cancer * Idiopathic iron deficiency * Chronic idiopathic thrombocytopenia * Atrophic gastritis * Helicobacter infected dyspepsia * Long term NSAIDs use Exclusion Criteria: * Pregnant * Previous proton pump inhibitor, antibiotics or anticoagulant use within 2 weeks * Previous stomach surgery * Severe ill patients (heart failure, hepatic failure, renal failure, hematologic disorder, severe psychologic or neurologic disorder) * Previous Helicobacter eradication * Allergy for Helicobacter eradication medicine

Locations (1)

Ajou University Hospital

Suwon, South Korea

RECRUITING

Outcomes

Primary Outcomes

Eradication rate of Helicobacter pylori

Time frame: one month

Central Contacts

Ki Myung Lee, M.D., Ph.D.

CONTACT

82-31-219-6939 lkm5104@ajou.ac.kr

Sun Gyo Lim, M.D.

CONTACT

82-31-219-6939 mdlsk75@hanmail.net

Data from ClinicalTrials.gov

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