The purpose of the study is to determine whether there are differences in bioelectrical function (measured by amplitude integrated electroencephalography) and brain oxygenation (measured by near infrared spectroscopy) while and after instillation of two different surfactant preparations.
Patients randomized to one of the treatment groups: 1) SRT with porcine preparation - poractant alfa; 2) SRT with bovine preparation - beractant. Continuous monitoring and simultaneous recordeding of 1) saturation (SpO2) and heart rate (HR) measured with pulse oximetry, cerebral tissue oxygenation measured with near-infrared spectroscopy, amplitude-integrated electroencephalography.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
22
aEEG and NIRS monitoring during poractant alfa instilation
aEEG and NRs monitoring during beractant instillation
Department of Neonatology
Poznan, Great Poland, Poland
Cerebral oxygenation
Cerebral tissue oxygenation measured with near-infrared spectroscopy
Time frame: 4 hours after surfactant instillation
Brain bioelectrical activity
Brain bioelectrical activity measured with amplitude-integrated electroencephalography (aEEG)
Time frame: 4 hours after surfactant instillation
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