Evaluation of Dry Eye and Meibomian Gland Dysfunction After Cataract Surgery

N/ACompletedNCT01942642

Yonsei University48 enrolled

Overview

Meibomian gland dysfunction (MGD) is a common and important disease has been investigated the pathophysiology, diagnosis, treatment modalities of MGD, however, the changes of MGD after the cataract surgery, the most popular surgery to ophthalmologist, had not been evaluated. The investigators evaluated parameters related with MGD including lid margin abnormalities, meibomian gland expressibility and meibography before and after surgery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Meibomian Gland Dysfunction

Eligibility

Sex: ALLMin age: 45 YearsMax age: 88 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1\. Patients scheduled for cataract surgery Exclusion Criteria: 1. other comorbid ocular diseases such as ocular allergies. 2. continuous use of topical ocular medications before surgery 3. histories of ocular surgery, or ocular injury 4. Already had severe obstructive MGD before surgery, abnormal findings on lid margin (\> 3 positive findings), reduced meibum expression (\> grade 2), and obstructed gland dropout (meibography score \> 3)

Outcomes

Primary Outcomes

Ocular parameters

Ocular symptom score, lid margin abnormalities, superficial punctuate keratopathy, tear film break-up time, Shirmer's test, lower tear meniscus height (TMH), depth (TMD), and area (TMA), meibum expressibility, and meibography score

Time frame: change of Ocular parameters from 1 to 3 months after cataract surgery

Data from ClinicalTrials.gov

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