This study will be an investigator-blinded, patient-blinded, assessor-blinded, parallel-group, randomized clinical trial. It aims to evaluate the efficacy of one-week twice-daily application of topical papaya leaf extract ointment compared to mupirocin ointment in achieving clinical cure among patients with impetigo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
128
St. Luke's Medical Center
Quezon City, NCR, Philippines
RECRUITINGClinical clearance after 1 week of treatment
Time frame: 1 week
time to clinical clearance
Time frame: 1 week
score in the 6-point grading system
The 6-point grading system will assess clinical response based on each of the following six paramaters. One point will be assigned for each of the following parameters present in a patient, with the maximum possible score on this grading system being 6. A patient need not satisfy all six parameters. A decrease in score on this grading system compared to baseline will indicate clinical improvement, while an increase in score will indicate clinical worsening. * erythema * edema * vesiculation * pustulation * crusting * scaling
Time frame: 1 week
change in size of lesion compared to baseline
Time frame: 1 week
presence or absence of recurrence on any part of the body 2 weeks after starting treatment
Time frame: 1 week
presence or absence of adverse events during treatment
Time frame: 1 week
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