Exercise Performance in Patients With Atrial Fibrillation

N/AUnknownNCT01943981

Incheon St.Mary's Hospital50 enrolled

Overview

Heart failure and stroke are the two major complication of atrial fibrillation. Current treatment for atrial fibrillation is so focused to stroke prevention, but the risk assessment for heart failure is less highlighted. The most of patients with atrial fibrillation have cardiac functional limitation of variable degree. We hypothesize that the exercise test would reveal the subclinical cardiac dysfunction, and might be helpful to classify the patients with atrial fibrillation according to their exercise capacity real cardiac function.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Atrial Fibrillation

Eligibility

Sex: ALLMin age: 30 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Nonvalvular chronic atrial fibrillation * Left ventricular ejection fraction \>40% Exclusion Criteria: * Acute decompensated heart failure within 30 days * unstable hemodynamic status * Significant coronary artery disease * Any condition interfering sufficient exercise * Valvular stenosis or regurgitation of moderate or severe degree * Obstructive or restrictive lung disease of moderate or severe degree * Active malignancy

Locations (1)

Incheon St.Mary's Hospital

Incheon, South Korea

Outcomes

Primary Outcomes

Exercise response patterns of heart rate and oxygen uptake

Time frame: At baseline

Secondary Outcomes

Composite cardiovascular events (all death, admission of heart failure, stroke/thromboembolism)

Time frame: Up to 2 years

Data from ClinicalTrials.gov

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