The malodour generation of a person's armpit is caused by the bacteria thriving on that armpit. In order to alter or reduce once bad body odour, the living microbial community on the armpit of a non-malodorous person will be transmitted (or up scaled and transmitted) to the armpit of a malodorous person. The odour is evaluated by a trained smelling panel, the bacteria living on the armpit is examined by means of molecular techniques. The microbial transplantation and its follow-up happens under the supervision of a medical doctor.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Every subject has 2 armpits; 1 armpit is treated, the other one is not treated. There is a microbial transplant from armpit bacteria.
Ghent University Hospital
Ghent, Belgium
Ghent University
Ghent, Belgium
Reduction of bad odour of the armpit.
Odour evaluation by a trained smelling panel. The measurements take place before (once), during the treatment week (5 times) and after the treatment (2x per week during 2 months).
Time frame: 24 evaluations in approximately 10 weeks.
Molecular characterisation of the bacterial community after microbial transplantation.
Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis. The measurements take place before (once), during the treatment week (5 times) and after the treatment (2x per week during 2 months).
Time frame: 24 evaluations in approximately 10 weeks.
Reduction of bad odour of the armpit over a longer period.
Odour evaluation by a trained smelling panel.
Time frame: after 4 months
Reduction of bad odour of the armpit over a longer period.
Odour evaluation by a trained smelling panel.
Time frame: after 6 months
Molecular characterisation of the bacterial community after microbial transplantation.
Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis.
Time frame: after 4 months
Molecular characterisation of the bacterial community after microbial transplantation.
Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis.
Time frame: After 6 months
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