Gene Expression in Patients With Epiretinal Membranes

N/AUnknownNCT01946451

Medical University of Silesia

Overview

The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in proliferative diabetic retinopathy. Possible correlations between messenger ribonucleic acid (mRNA) levels of these genes were also identified.

Study Type

OBSERVATIONAL

Conditions

Proliferative Diabetic Retinopathy

Eligibility

Sex: ALLMin age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Caucasian race, * both males and females, * aged ≥ 55 years, * suffering from idiopathic ERMs or secondary ERMs in proliferative diabetic retinopathy (PDR). * Presence of ERM was proven in optical coherence tomography (OCT) examination. Exclusion criteria: * aged \< 55 years, * systemic connective tissue disease, * active inflammatory process

Locations (1)

Medical University of Silesia

Katowice, Poland

Outcomes

Primary Outcomes

Gene expression in patients with idiopathic and secondary epiretinal membranes in proliferative diabetic retinopathy.

Time frame: The period between the diagnosis of the ERMs and the actual surgery for the condition was between 2 and 43 months.

Data from ClinicalTrials.gov

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