Specific Enteral Nutrition in Malnourished, Dialysis Patients With Chronic Kidney Disease. Efficacy, Safety, Quality of Life

Inclusion Criteria: * Chronic kidney disease patient on hemodialysis for at least 3 months, with a minimum of three hemodialysis sessions of 4 hours per week * Patients aged 18 years * Written, free and informed consent given by the Patient * Patient insured under the social security system or equivalent * Patients who did not receive enteral nutrition during the 3 months preceding inclusion ; taking an oral nutritional supplement, or per-dialytic parenteral nutrition or total parenteral nutrition is not a criterion of non-inclusion * Patient in a state of malnutrition * defined by the presence of at least 3 out of 5 of the following criteria : * weight loss greater than 10% observed in the last six months * serum albumin \<35 g / l * serum Prealbumin \<300 mg / l * BMI \<20 * NPNA \<1 g / kg / day for 2 consecutive months and * presenting * food intake \<20 kcal / kg / day or * failure of other nutritional care methods, namely, oral nutritional supplements and / or peridialytic parenteral nutrition, or total parenteral nutrition * lack of compliance after one month, to the nutritional care methods mentioned above. • Patients for whom the decision to prescribe enteral feeding was previously taken Exclusion Criteria: * Patients with a history of intolerance to enteral feeding * Index Kt/Veq (balanced) \< or = 1.2 or index Kt/Vsp (single pool) \< or = 1.4 according to the method used * Patients with a disease compromising the short-term (4-6 months) prognosis (cancer or other disease in the terminal phase) * Pregnant Patient * Patient with a known allergy to at least one of the following : milk protein, soy, fish * Patient whose digestive tract is not functional or patient in shock * Patient protected under guardianship * Patient in exclusion period after participation in another clinical trial.