Effect of Garlic Tablet Some Indicators Related to Atherosclerosis

N/ACompletedNCT01948453

Shahid Beheshti University56 enrolled

Overview

The purpose of this study is to determine whether garlic in adjunct to conventional medical treatment is effective in improving carotid intima media thickness (CIMT), Flow mediated dilation (FMD) and plasma lipid profile or c-reactive protein of coronary artery disease (CAD) patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

QUADRUPLE

Enrollment

Conditions

Coronary Artery Disease

Interventions

GarlicDIETARY_SUPPLEMENT

Garlic tablet in adjunct to medical treatment

Eligibility

Sex: ALLMin age: 25 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * angiography confirmed coronary artery disease * lack of consistent use of the garlic in the last month Exclusion Criteria: Change in type of medication during study

Locations (1)

Rajaei Cardiovascular, Medical & Research Center

Tehran, Iran

Outcomes

Primary Outcomes

Carotid Intima Media Thickness

Change from baseline and compared to placebo group in Carotid Intima Media Thickness at 12 weeks

Time frame: 12 weeks

Secondary Outcomes

Flow-mediated dilatation

Change from baseline and compared to placebo group in Flow-mediated dilatation at 12 weeks

Time frame: 12 weeks

Data from ClinicalTrials.gov

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