Our pilot results showed that meperidine reduce patient discomfort during EGD (esophagogastroduodenoscopy). But many patients can tolerate EGD well without any sedative agents. So the investigators target the use of meperidine on patients expected to have poor tolerance in this study, which includ young females with high anxiety level and patients with prior poor tolerance. The investigators test the hypothesis that meperidine improves tolerance and alleviates discomfort for patients expected to have poor tolerance during diagnostic EGD.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
QUADRUPLE
Enrollment
110
Buddhist Dalin Tzu Chi General Hospital
Chiayi City, Taiwan, Taiwan
discomfort score during esophageal intubation
self-reported discomfort score during esophageal intubation, assessed with a 0 to 10 (0 = none; 10 = unbearable) visual analog scale (VAS).
Time frame: 10 minutes
patient discomfort score during the procedure
Time frame: 10 minutes
patients satisfaction score
Time frame: 10 minutes
patient tolerance score evaluated by the endoscopist
Time frame: 10 minutes
endoscopist satisfaction score
Time frame: 10 minutes
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