The aim of this randomised case-controlled trial is to investigate whether ablation of incompetent perforating vein in addition to ablation of truncal vein reduces the rate of recurrent varicose veins post-treatment compared with patients who only have ablation of the truncal vein, who are left with untreated incompetent perforating veins.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
190
Endovenous laser ablation of great saphenous vein
removal of incompetent veins
TRansluminal Occlusion of Perforators (TRLOP) closure of incompetent perforators.
The Whiteley Clinic
Guildford, United Kingdom
Differences in the level of significant recurrence between the two treatment pathways
Differences in the level of significant recurrence between the two treatment pathways at each follow up. Significant recurrence would be indicated if the participant demonstrates varicose veins greater than 3mm in diameter, varicose veins associated with thrombophlebitis or skin changes such as venous eczema, red skin or brown skin overlying the veins which require further treatment.
Time frame: Four weeks, three months, six months, one year, two years, three years, four years and five years post-surgery
Differences in insignificant recurrence between the two treatment pathways
Evidence of insignificant recurrence - thread veins, reticular veins or varicose veins less than 3mm in diameter.
Time frame: Four weeks, three months, six months, one year, two years, three years, four years and five years post-surgery
Patient reported symptom severity
Patient reported symptom severity - the Aberdeen questionnaire
Time frame: Four weeks, three months, six months, one year, two years, three years, four years and five years post-surgery
Patient reported quality of life
Patient reported quality of life - The Chronic Venous Insufficiency Questionnaire (CIVIQ)
Time frame: Four weeks, three months, six months, one year, two years, three years, four years and five years post-surgery
Patient satisfaction with treatment.
Time frame: Four weeks, three months, six months, one year, two years, three years, four years and five years post-surgery
Clinician reported severity of symptoms
CEAP and VCCS scores
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: Four weeks, three months, six months, one year, two years, three years, four years and five years post-surgery