The objective of this randomized, controlled feeding study is to investigate the potential health benefits of a pecan-containing diet. The investigators hypothesize the chronic consumption of pecans will improve an array of biomarkers related to cardiovascular disease and type 2 diabetes risk, including indices of oxidative stress, antioxidant activity, inflammation, endothelial function, and insulin resistance when compared with a control diet that is absent nuts.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
28
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University
Boston, Massachusetts, United States
Change in biomarkers of oxidative stress compared with control diet
Time frame: Baseline and 4 weeks
Change in biomarkers of inflammation compared with control diet
Time frame: Baseline and 4 weeks.
Change in biomarkers of endothelial function compared with control diet
Time frame: Baseline and 4 weeks.
Change in biomarkers of antioxidant activity compared with control diet
Time frame: Baseline and 4 weeks
Change in biomarkers of insulin resistance compared with control diet
Time frame: Baseline and 4 weeks
Change in blood pressure compared with control diet
Time frame: Baseline and 4 weeks
Change in plasma lipid profile compared with control diet
Time frame: Baseline and 4 weeks.
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