In the FINS study we test - in a randomized non blinded intervention study- the hypothesis that increased intake of salmon will improve cognitive performance of children aged 4 years to 6 years in the Munich area (Germany), who habitually consume little fish.
Long chain polyunsaturated fatty acids (LC-PUFA) of the n-3 series, eicosapentaenoic acid (EPA) and most prominently docosahexaenoic acid (DHA), are considered important for neural development during pre- and postnatal development.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
Meals containing salmon
No fish meals
Div. Metabolic and Nutritional Medicine Dr. von Hauner Children's Hospital Univ. of Munich Medical Centre
Munich, Bavaria, Germany
Change in Cognitive Performance
Time frame: Change from baseline at 4 months later
Change of cheek cell glycerophospholipids docosahexaenoic and eicosapentaenoic percentage
Time frame: Change from baseline at 4 months later
Change of red blood cell fatty acids (omega-3 index),plasma phospholipid species and plasma vitamin D3
Time frame: Change from baseline at 4 months later
Change of iodine levels in urine
Time frame: Change from baseline at 4 months later
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