Assessment of a Probiotic to Treat Gingivitis in Pediatric Patients

Inclusion criteria: * Are male or female between the ages of 11 to 18 years * Have mild to moderate gingivitis as determined by dentist (GI of at least 1 to a maximum of 2) * Are undergoing fixed orthodontic therapy on both arches with attachments on at least 20 teeth including bonded 1st molars for a minimum of 5 months. * Have fully erupted teeth #16, #21, #23, #36, #41, and #43 * Are caries inactive prior to study initiation. * Are in a healthy systemic condition * Have not used any antimicrobial mouth rinses, probiotics (unrelated to the study), antibiotics or anti-inflammatories medications with one month prior to and during the study * Whose legal guardian has given informed consent to participate in the study and must be able to communicate in English Exclusion Criteria: * Unable to make informed consent * Subjects with allergies to milk or milk products, gluten or soy or any other ingredients present in the lozenge * Immune compromised * Major underlining medical condition * Pregnancy * History of smoking or alcohol consumption * Have major dental conditions such as periodontal disease, dental caries and/or xerostemia or systemic diseases which could directly or indirectly affect plaque formation * Use of medications within 1 month (antibiotics, anti-inflammatory, mouth rinses) that can influence the outcome. * Ongoing or recent (within 1 month) use of probiotics unrelated to the study * Have within the past 30 days experienced any nausea, fever, vomiting, bloody diarrhea or severe abdominal pain