Evaluate the long term efficacy and side effects of oxybutynin in the treatment of hyperhidrosis.
This retrospective study aims to evaluate the medical charts of patients who were treated with oxybutynin for at least six months for primary hyperhidrosis. The investigators variables of interest are: (1) quality of life before pharmacological therapy and after six weeks, (2)self-perception of improvement in hyperhidrosis after six weeks of treatment and on last visit (whenever this occur, as long as this happens after six months), (3) side effects related to drug use.
Study Type
OBSERVATIONAL
Enrollment
1,100
All patients are treated with oxybutynin for hyperhidrosis. Usual maintenance dose is 10mg/day, but dose may vary according to weight, efficacy and side effects. Our standard protocol starts with 2.5mg/day in the first 7 days, progresses to 5mg/day for 14 days and then reaches the usual maintenance dose of 10mg/day afterwards.
Hospital Israelita Albert Einstein
São Paulo, São Paulo, Brazil
Quality of life
Evaluate the Quality of life (using a standardized questionnaire for hyperhidrotic patients) before pharmacological treatment
Time frame: 1 day before treatment
Quality of life
Evaluate the Quality of life (using a standardized questionnaire for hyperhidrotic patients) after 42 days of treatment
Time frame: Forty-two days after treatment
Perception of improvement in excessive sweating
We want to analyze the patient's self perception (grades 0 to 10) of amelioration in sweating after forty-two days of treatment
Time frame: After 42 days of treatment
Perception of improvement in excessive sweating
We want to analyze the patient's self perception (grades 0 to 10) of amelioration in sweating on the last medical visit (whenever this happens).
Time frame: 1 day (On the last medical visit)
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