Stereotactic Directional Vacuum-Assisted Breast Biopsy

N/ACompletedNCT01957020

National Taiwan University Hospital130 enrolled

Overview

Stereotactic directional vacuum-assisted breast biopsy (ST DVAB) is a standard biopsy procedure for suspicious findings on mammograms in Western countries for more than 10 years \[1-3\], it has replaced the needle localization (NLOC) excisional biopsy for the lesions alike and was reported to feature a high sensitivity, very low delayed false-negative rate (less than 2%)\[4,5\]. Moreover, it causes less scarring, less psychologic stress to patients and less morbidity compared with needle localization excisional biopsy \[6,7\]. However, its sensitivity, accuracy has seldom been reported in Asian countries \[8\] , since most Asian women have different breast parenchyma pattern, different breast cancer prevalence. Therefore, we retrospectively reviewed outcomes of the two groups of patients receiving either ST DVAB or NLOC excisional biopsy, trying to investigate if ST DVAB can be an effective alternative to NLOC excisional biopsy in our country.

Study Type

OBSERVATIONAL

Enrollment

130

Conditions

Breast Cancer Stereotactic Directional Vacuum-assisted Breast Biopsy Female Adult Patients

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * The indication for ST DVAB was lesions with suspicious nature for malignancy seen on mammograms which biopsy is necessitated for tissue proof, or probably benign or benign appearing lesions seen on mammograms but patients or clinicians requested biopsy Exclusion Criteria: \-

Outcomes

Primary Outcomes

The sensitivity of stereotactic vacuum assisted breast biopsy for breast cancer diagnosis

the aforementioned outcome measure-"sensitivity"- is the probability of the stereotactic vaccum assisted breast biopsy can correctly diagnose the breast cancer. And according to statistical definition, it is defined as- for those breast cancer cases, how many of them can be correctly diagnosed by stereotactic breast biopsy.

Time frame: up to 5 years ( July 2008 to June 2013)