Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of Single Escalating Doses of BI 1034020 Administered Intravenously or Subcutaneously to Male Healthy Volunteers

Inclusion criteria: 1. Healthy males based upon a complete medical history, including a physical examination, vital signs (blood pressure, pulse rate), 12-lead electrocardiogram, and clinical laboratory tests 2. Age within the range of 18 to 40 years 3. Body mass index within the range of 18.5 and 29.9 kg/m2 4. Signed and dated written informed consent prior to admission to the study in accordance with GCP and local legislation. Exclusion criteria: 1. Any finding in the medical examination (including blood pressure, pulse rate or electrocardiogram) deviating from normal and judged clinically relevant by the investigator. Pulse rate outside the range of 50-90 bpm or blood pressure outside the ranges of 90-140 for systolic and 50-90 mmHg for diastolic blood pressure if confirmed by repeat measurement 2. Any evidence of a clinically relevant concomitant disease. 3. Gastrointestinal, hepatic, renal, respiratory, cardiovascular, metabolic, immunological or hormonal disorders. 4. Surgery of the gastrointestinal tract (except appendectomy). 5. Diseases of the central nervous system (such as epilepsy) or psychiatric disorders or neurological disorders. 6. History of relevant orthostatic hypotension, fainting spells or blackouts. 7. Chronic or relevant acute infections.