This study is To confirm the efficacy of Naftopidil for reducing discomfort of ureteral stent after urinary stone surgery.
1. Enrollment 1. patients underwent Double-J ureteral stent indwelling after urological surgery during less than 15 days 2. patients aged more than 20 years 2. Randomization 1. naftopidil 75 mg qd or placebo until Double-J stent removal 2. Standard treatment with pain-killers on demand were also applied.(aceclofenac) 3. Follow-up to the day of Double-J stent removal (Evaluation should be done at stent removal)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
100
Seoul National University Bundang Hospital
Seongnam, Kyunggi, South Korea
Kangwon National University Hospital
Chuncheon, South Korea
Donguk University Ilsan Hospital
Goyang, South Korea
Seoul National University Hospital
Seoul, South Korea
Ureteral Stent Symptom Questionaire(USSQ) urinary symptom score
DJ stent removal should be done between study day 5 and 15.
Time frame: at the day of DJ stent removal, an expected average of 10 days (range: 5-15 days)
USSQ body pain score
Time frame: at the day of DJ stent removal, an expected average of 10 days (range: 5-15 days)
USSQ general health score
Time frame: at the day of DJ stent removal, an expected average of 10 days (range: 5-15 days)
USSQ work performance score
Time frame: at the day of DJ stent removal, an expected average of 10 days (range: 5-15 days)
USSQ sexual matters score
Time frame: at the day of DJ stent removal, an expected average of 10 days (range: 5-15 days)
International Prostate Symptom Score(IPSS), QoL score
Time frame: at the day of DJ stent removal, an expected average of 10 days (range: 5-15 days)
Total analgesics use
Time frame: at the day of DJ stent removal, an expected average of 10 days (range: 5-15 days)
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National Medical Center
Seoul, South Korea
Seoul National University Boramae Hospital
Seoul, South Korea