A Non-Interventional Study of Patients With Persistent Symptoms of Schizophrenia to Describe Medical Resource Utilization and Burden of Illness

N/ACompletedNCT01959659

Hoffmann-La Roche1,431 enrolled

Overview

This non-interventional, cross-sectional survey and retrospective review will evaluate the medical resource utilization and burden of illness in patients who have persistent symptoms of schizophrenia despite receiving adequately dosed antipsychotic treatment and who have not had an acute exacerbation in the 3 months prior to enrolment. Medical records will be reviewed for a minimum of 3 months and up to 12 months prior to screening. Data collection at a single visit will include rating scales and questionnaires that reflect the clinical status and the quality of life of the patients and the economic impact of schizophrenia.

Study Type

OBSERVATIONAL

Enrollment

1,431

Conditions

Schizophrenia

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients, \>/= 18 years of age * Patients who have a clinical diagnosis of schizophrenia as documented in their medical records * Patients who, in the opinion of the investigator, have had on-going, persistent symptoms of schizophrenia for at least the last 3 months prior to enrolment * Patients who, in the opinion of the investigator, have been prescribed adequate doses of antipsychotic treatment for at least the last 3 months * Patient has adequate spoken local language Exclusion Criteria: * Acute exacerbation of schizophrenia within the last 3 months prior to enrolment * Enrolment in an interventional study

Locations (107)

Unnamed facility

Epping, New South Wales, Australia

Unnamed facility

Everton Park, Queensland, Australia

Unnamed facility

Brno, Czechia

Unnamed facility

Brno, Jihormoravsky Kraj, Czechia

Unnamed facility

Hradec Králové, Czechia

Unnamed facility

Olomouc, Czechia

Unnamed facility

Pilsen, Czechia

Unnamed facility

Prague, Czechia

Unnamed facility

Prague, Czechia

Unnamed facility

Prague, Czechia

...and 97 more locations

Outcomes

Primary Outcomes

Medical resource utilization (in-/out-patient hospital services, community-based day service, other health care contacts) of patients with persistent symptoms of schizophrenia

Time frame: in the 3 to 12 months prior to screening

Secondary Outcomes

Level/severity of schizophrenia symptoms: Clinical rating scales scores (PANSS, CGI-S, PSP, WoRQ, NSA-4, HoNOS)

Time frame: Observational visit Day 1

Patient health-related quality of life (HRQoL) questionnaires

Time frame: Observational visit Day 1

Caregiver's burden as assessed by questionnaires

Time frame: Observational visit Day 1