To evaluate the additive values of T1 mapping in patients with acute myocarditis.
Cardiac magnetic resonance (CMR) is an established non-invasive diagnostic tool for acute and chronic myocarditis. Established CMR criteria for diagnosing myocarditis are edema on black-blood T2-weighted imaging, relative contrast enhancement seen on T1-weighted imaging for assessment of hyperemia, and late contrast-agent enhancement seen with inversion recovery late enhancement technique for visualization of myocardial fibrosis. Recently, tissue characterization based on calculation of myocardial T1 relaxation time (T1 mapping) as well as T1-derived extracellular volume fraction has become available. Recently, reference values for myocardial T1 relaxation times at 3T for healthy volunteers were published for CMR. However, to date no comprehensive data for multiparametric CMR in patients with suspected myocarditis at 3 Tesla is available. Therefore, the purpose of this prospective study was to evaluate the diagnostic value of CMR at 3T in patients with suspected acute myocarditis using a multiparametric CMR approach including T1 mapping as novel tool for tissue characterization. CMR will be performed within 7 days after hospital admission for "suspected acute myocarditis".
Study Type
OBSERVATIONAL
Enrollment
66
University of Bonn
Bonn, North Rhine-Westphalia, Germany
T1 relaxation times
quantification of T1 relaxation times
Time frame: time of CMR, CMR will be performed within 7 days after hospital admission for "suspected acute myocardtitis".
Extracellular volume (ECV)
calculation of extracellular volume based on T1 relaxation time
Time frame: time of CMR, CMR will be performed within 7 days after hospital admission for "suspected acute myocardtitis".
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