Effect of 4 Weeks of Shuttle Run Training on Insulin Sensitivity in Sedentary Men

N/ASuspendedNCT01962857

University of Glasgow30 enrolled

Overview

A number of studies have shown that short duration, high intensity interval training can improve health-related outcomes, such as insulin sensitivity and cardiorespiratory fitness. However, these often use specialized equipment, such as cycle ergometers, which makes it difficult to roll these interventions out for wide-scale use in the general population. This study aims evaluate the effects of a high intensity shuttle running intervention on insulin sensitivity, fitness and related cardiometabolic risk factors in men who are currently inactive. Participants will be randomized into intervention (4 weeks of shuttle running) and control groups. We hypothesize that the shuttle running programme will result in improved insulin sensitivity, fitness and increased fat oxidation at rest compared with the control group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Insulin Resistance Obesity Metabolic Syndrome

ExerciseBEHAVIORAL

4-week supervised high intensity shuttle running intervention, 3 sessions per week (12 sessions in total)

Eligibility

Sex: MALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * male * 18-40 years * undertaking \< 1 hour per week of planned exercise Exclusion Criteria: * BMI \> 35 kg/m2 * Blood pressure \> 160/90 mm Hg (on anti-hypertensive medication) * history of established coronary heart disease * family history of early cardiac death (\<40 years)

Locations (1)

University of Glasgow

Glasgow, United Kingdom

Outcomes

Primary Outcomes

Insulin sensitivity

Assessed from glucose and insulin concentrations in fasted state and during oral glucose tolerance test.