Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A alternative is the application of low dose mivacurium, reversed with neostigmine. The investigators compare the intubating conditions, incidence of postoperative myalgia (POM), patient satisfaction and the postoperative performance with respiration exercise device for these two muscle relaxants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
Anaesthesia was induced and maintained with propofol(1-2mg/kg and 5mg/kg/h) and remifentanil (1µg/kg and 0,2µ/kg/min). The study arm is immobilized and a dual electrode for peripheral nerve stimulation is placed over the ulnar nerve near the wrist. Neuromuscular monitoring is performed with accelerometry. the patients receive the muscle relaxant according to the study group.
Anaesthesia was induced and maintained with propofol(1-2mg/kg and 5mg/kg/h) and remifentanil (1µg/kg and 0,2µ/kg/min). The study arm is immobilized and a dual electrode for peripheral nerve stimulation is placed over the ulnar nerve near the wrist. Neuromuscular monitoring is performed with accelerometry. the patients receive the muscle relaxant according to the study group.
Dr. Horst Schmidt Klinik GmbH
Wiesbaden, Germany
Intubating condition
For measuring the intubation conditions the scoring system proposed for Good clinical Research Practice using the following variables is used: conditions of inserting the rigid bronchoscope, vocal cord position and coughing
Time frame: After induction of general anaesthesia (after 3-5 minutes)
Postoperative Myalgia
The severity of POM was measured using a four point scale: 0=no myalgia 1. minor pain limited to one area of the body 2. muscle pain or stiffness noticed spontaneously by the patient, which may have required analgesic therapy 3. generalized, severe or incapacitating discomfort
Time frame: 72 hours after intervention
postintervention performance with a expiration exercise device
The performance with a respiration exercise device, which measures the expirational volume, before and after intervention.
Time frame: 72 hours after intervention
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.