Characterization of Lung Function Profile of Inhaled Tiotropium + Olodaterol Fixed Dose Combination Compared to Fluticasone Propionate + Salmeterol Fixed Dose Combination in COPD Patients

Inclusion criteria: 1. Diagnosis of chronic obstructive pulmonary disease 2. Relatively stable airway obstruction with a post-bronchodilator 30% \</= Forced Expiratory Volume in 1 second (FEV1)\<80% of predicted normal and a post-bronchodilator FEV1/(Forced Vital Capacity)FVC \<70% 3. Male or female patients, 40 years of age or older 4. Smoking history of more than 10 pack years 5. Ability to perform technically acceptable pulmonary function tests and maintain records 6. Ability to inhale medication in a competent manner from the RESPIMAT Inhaler, Accuhaler and from a metered dose inhaler (MDI) Exclusion criteria: 1. Significant disease other than COPD 2. COPD exacerbation that required treatment with antibiotics, systemic steroids (oral or iv) or hospitalization in the last 3 months. 3. Clinically relevant abnormal lab values 4. History of asthma 5. Diagnosis of thyrotoxicosis 6. Diagnosis of paroxysmal tachycardia 7. History of myocardial infarction 8. Unstable or life-threatening cardiac arrhythmia 9. Hospitalization for heart failure within the past year 10. Known active tuberculosis 11. malignancy for which patient has undergone resection, radiation therapy or chemotherapy within last five years 12. History of life-threatening pulmonary obstruction 13. History of cystic fibrosis 14. Clinically evident bronchiectasis 15. History of significant alcohol or drug abuse 16. History of thoracotomy with pulmonary resection 17. oral or patch ß-adrenergics 18. Oral corticosteroid medication within 6 weeks prior to Visit 1 19. Regular use daytime oxygen therapy for more than one hour per day 20. Pulmonary rehabilitation program in the six weeks prior to the screening visit 21. Investigational drug within one month or six half lives (whichever is greater) prior to screening visit 22. Known hypersensitivity to ß-adrenergic drugs, BAC, EDTA 23. Pregnant or nursing women