DermACELL in Subjects With Chronic Wounds of the Lower Extremities

Inclusion Criteria: * Male and female between the ages of 21 and 80 that are able to provide informed consent, are available for weekly clinic visits and are willing to comply with off-loading requirements of treatment; * If diabetic, have been on a stable dose of medication to treat diabetes for less than 30 days; * Have a DFU that has been present for at least 30 days or have a VSU that has been present for at least 60 days; Exclusion Criteria: * Have a DFU or VSU that is infected; * Are pregnant or lactating; * Have an allergy or are sensitive to one of the following antibiotics: lincomycin, gentamicin, polymyxin B, or vancomycin; * Have a sensitivity to polysorbate 20, N-lauroyl sarcosinate, benzonase or glycerol; * Have had a HbA1c level greater than 12% within the past 90 days; * Have liver function tests or kidney function tests that are very elevated; * Have a known or suspected disease of the immune system; * Have had surgery in the past 30 days to increase blood flow into your leg or foot; * Have cancer or a connective tissue disease (i.e. lupus, rheumatoid arthritis); * Have undergone wound healing treatment with a living skin equivalent (i.e., Dermagraft®, Apligraf®, TheraSkin®, Oasis®, GraftJacket®, Integra®, Alloderm®) or topical growth factors in the last 4 weeks; * Have active Charcot disease, a weakening of the bones in the foot that can occur in people who have significant nerve damage (neuropathy);