Effects of Tribulus Terrestris in Women With Hypoactive Sexual Desire Disorder

Phase 4CompletedNCT01971099

Federal University of Minas Gerais44 enrolled

Overview

Hypoactive Sexual Desire Disorder (HSDD) is the most prevalent female sexual dysfunction in society and is strongly linked to the quality of life of women. The androgen hormones decline over age in the premenopausal period, which occurs around 20 years. Tribulus terrestris is a plant native to India, recommended in the treatment of infertility, low libido and impotence. Its main active ingredient is the protodioscin, which has been attributed to an increase in testosterone levels and improved sexual function. The aim of this study is to evaluate the effects of Tribulus Terrestris in premenopausal women with HSDD.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Hypoactive Sexual Desire Disfunction

Interventions

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * regular menstrual cycle * with no use of hormonal contraception within the last 3 months * without any medication, drugs or alcohol. * Healthy patients without systemic or psychiatric disease Exclusion Criteria: * Patients with amenorrhea and/or pregnant. * Patients who underwent bilateral oophorectomy. * Patient smoker (10 cigarettes per day). * Patients with blood pressure \> 160/90 mm Hg. * Patient with breast or endometrial carcinoma. * Patients with a history of myocardial infarction. * Patient with Diabetes. * Patient with vaginal bleeding from any source. * Patients with hepatic injury. * Patients with active thrombophlebitis or thromboembolic disorders recent * Patients with interpersonal relationship problems with your relationship or partner * Patients with sexual problems from your partner

Outcomes

Primary Outcomes

Sexual Desire

we will use the "Quotient Sexual - Version Feminine (QS-F) brazilian questionary to make the evaluation

Time frame: 120 days

Secondary Outcomes

serum levels of prolactin and thyroid-stimulating hormone (TSH)

blood test