Safety, Tolerability, PK & PD Study of JTZ-951 in Anemic Subjects With End-stage Renal Disease

Inclusion Criteria: * Subjects who have ESRD and have been receiving maintenance hemodialysis for at least 12 weeks prior to the Screening Visit * Body weight (post-dialysis weight) greater than 45.0 kg and a body mass index between 20.0 and 40.0 kg/m2 (inclusive) at the Screening Visit * Hemoglobin value as defined in the protocol * Meet the erythropoiesis-stimulating agent (ESA) therapy criteria at the Screening Visit as defined in the protocol Exclusion Criteria: * Transferrin saturation and ferritin levels at the Screening Visit as defined in the protocol * Anemia due to known causes other than chronic kidney disease * Known history of hyporesponsiveness to ESAs * Acute coronary syndrome (e.g., myocardial infarction) within 1 year prior to Screening visit