DLBS1449 in Diabetic Patients With Low HDL

Inclusion Criteria: * Male or female 21 - 70 years. * Have been diagnosed diabetes mellitus and being treated with lifestyle intervention for at least 1 month prior to screening, with or without antidiabetic agents. * HDL-cholesterol level of \< 35 mg/dL. * Triglycerides level of \< 200 mg/dL. * Adequate liver and renal function. * Statin and/or fenofibrate therapy should have been being regularly taken for \>=3 months at stable dose (ONLY for subjects currently under statin and/or fenofibrate therapy). * Able to take oral medication. Exclusion Criteria: * Pregnant or breast-feeding women or willing to be pregnant. * Symptomatic congestive heart failure, unstable angina pectoris, or cardiac arrhythmia. * Uncontrolled hypertension (SBP \> 160 mmHg and/or DBP \> 100 mmHg). * Any other disease state, including chronic/acute systemic infections, uncontrolled illnesses or other chronic diseases, which judged by the investigator, could interfere with trial participation or trial evaluation. * Concurrent treatment with systemic corticosteroids or herbal (alternative) medicines. * Known allergic or hypersensitive to drugs contain similar active substance with the study medication. * Participation in any other clinical studies within 30 days prior to screening.