A Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ZYD1, Following Subcutaneous Administration in Healthy Volunteers

Inclusion Criteria: 1. Age: 18-45 years 2. Mentally, physically, and legally eligible to give informed consent 3. Male and female volunteers weighing between 50-75 kg and 45-75 kg respectively 4. Ability to communicate effectively with the study personnel 5. Willingness to adhere to the protocol requirements 6. For gender effect study, only females with history of sterility or at least 1 year menopause or use of long acting nonhormonal contraceptive measures (e.g., intrauterine device) will be recruited. Exclusion Criteria: 1. Presence or history of hypersensitivity to any of the active or inactive ingredients of ZYD1 formulation 2. Presence or history of pancreatitis at any time (Serum Amylase/Serum Lipase more than upper normal limit (UNL)) 3. Presence or history of severe gastrointestinal disease in the last 6 months 4. Presence or history of renal insufficiency at any time (serum creatinine above the upper limit of the reference range) 5. Active liver disease and/or liver transaminases greater than 1.5 X UNL 6. Subject with personal or family history of medullary thyroid cancer 7. Subject with personal or family history of multiple endocrine neoplasia syndrome type 2 8. Subject with serum calcitonin \>50 ng/L 9. History or presence of other systemic disorders or diseases (e.g., respiratory, gastrointestinal, endocrine, immunological, dermatological, neurological, psychiatric disease or any other body system involvement) 10. Abnormal bleeding time (BT), clotting time (CT), prothrombin time (PT), and activated partial prothrombin time (APTT) tests on the day of check in 11. History or presence of any medication in the last 14 days including any medication known to interact with the Cytochrome P (CYP) 450 system 12. History or presence of significant alcoholism or drug abuse within the past 1 year 13. History or presence of significant smoking (more than 10 cigarettes per day) or consumption of tobacco products (more than 10 times per day) 14. Difficulty with donating blood 15. Systolic blood pressure more than 140 mmHg and less than 100 mmHg and diastolic blood pressure more than 90 mmHg and less than 60 mmHg 16. Pulse rate less than 60/minute and more than 100/minute 17. Any clinically significant abnormal X-ray or laboratory findings during screening 18. History or presence of any clinically significant electrocardiogram (ECG) abnormalities during screening 19. Major illness and/or major surgery in last 3 months 20. Volunteers who have participated in any drug research study other than the present trial within past 3 months 21. Volunteers who have donated one unit (350 ml) of blood in the past 3 months 22. For gender effect study, female volunteers with following criteria will not be recruited: * History of pregnancy or lactation in the past 3 months * Fertile female volunteers not protected against pregnancy by adequate long-term anti-fertility device or history of less than 1 year of menopause * Using hormonal contraceptives * Using hormone replacement therapy * Unable to give assurance for protection against pregnancy for 3 months after the participation in this trial * Positive urine pregnancy test on the day of check-in