Effect of Supragingival Irrigators Containing Chlorhexidine on Oral Health in Blood Dyscrasia

Phase 2CompletedNCT01974401

Mashhad University of Medical Sciences20 enrolled

Overview

in this study , effectiveness of supragingival irrigators containing chlorhexidine is compared with routine oral health measures in patients with blood dyscrasia whom can not use effective oral health measures(e.g brushing ) due to their systemic condition(e,g,neutropenia ,thrombocytopenia,..)

Since some patients with hematologic malignancies cannot brush effectively and are at increased risk of bleeding and infection due to severe neutropenia and thrombocytopenia we want to access whether a none invasive method ( water jet systems containing chlorhexidine ) Can help this patients to get better oral health indexes in comparison with routine oral health measures in these type of patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Severe Neutropenia Thrombocytopenia Chemotherapy Blood Dyscrasia Patients

Interventions

supragingival irrigators containing chlorhexidineDEVICE

patients received irrigation by oxyjet supra gingival irrigators containing chlorhexidine for at least 3 minutes for all dentulous regions of jaws which was performed by researchers once daily.

Eligibility

Sex: ALLMin age: 12 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: patients with a blood dyscrasia, severe neutropenia and thrombocytopenia, absence of periodontitis, absence of any oral mucosal lesion in onset of study, patient consent Exclusion Criteria: diabetes mellitus, observation of any side effect (resulted from the device), severe oral mucositis in intervention group(grade 3 and4 WHO), edentulousness, intolerance of device in severely malaise patients, patient death

Locations (1)

Oral Medicine Department of Mashhad dental School,Oral and Maxillofacial diseases research center

Mashhad, Razavi Khorasan Province, Iran

Outcomes

Primary Outcomes

improvement in oral health status

improvement of oral health was measured by oral health index simplified(OHI-S)

Time frame: 3 weeks

Secondary Outcomes

incidence of oral mucositis

incidence of mucositis due to Who criteria explored by clinical examination

Time frame: 3 weeks

Data from ClinicalTrials.gov

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