Assessment of Early Treatment Response by Diffusion and Perfusion MRI in Patients With Brain Metastasis

N/ACompletedNCT01974804

Memorial Sloan Kettering Cancer Center30 enrolled

Overview

Magnetic resonance imaging (MRI) is a diagnostic study that makes pictures of organs of the body using magnetic field and radio frequency pulses that can not be felt. The purpose of this study is to determine if new imaging methods can help tumor evaluation in the brain. The extra images will be obtained using diffusion and perfusion MRI techniques to assess early treatment response in patients with brain metastasis, and will be compared to methods currently being used.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Brain Cancer

Interventions

MRIPROCEDURE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults aged 18 and over. * Patients/Subjects able to give informed consent * Patients/Subjects whose weight does not exceed 275 lbs. * Patient with metastatic brain tumors greater than or equal to 1.0 cm that will be treated with stereotactic radiosurgery and scheduled for an MRI scan as part of their routine care Exclusion Criteria: * Patients who are unwilling or unable to undergo MRI including patients with contra-indications to MRI such as the presence of cardiac pacemakers or non-compatible intracranial vascular clips.

Locations (1)

Memorial Sloan Kettering Cancer Center

New York, New York, United States

Outcomes

Primary Outcomes

feasibility of diffusion and perfusion magnetic resonance imaging (MRI)

This is a technology assessment protocol for response to treatment. The study is designed to assess the utility of the technology using a limited number of participants. We will assess whether the MR parameters are predictive markers of early response.

Time frame: 1 year

Data from ClinicalTrials.gov

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