This study is a multicenter, non-randomized, retrospective study to collect long term (5 years post-transplant) clinical outcome data to test whether the results of the noninvasive immune monitoring test strategy performed in the parent study (CTOT-01, NCT00308802) in first six-month post-transplant is predictive of 5-year outcomes. Each center will complete a retrospective chart review for the data on patient survival, graft survival and renal function.
Study Type
OBSERVATIONAL
Enrollment
184
Yale University School of Medicine
New Haven, Connecticut, United States
Emory University
Atlanta, Georgia, United States
Mount Sinai School of Medicine
New York, New York, United States
University Hospitals of Cleveland
Cleveland, Ohio, United States
Cleveland Clinic Foundation, Glickman Urological Institute
Cleveland, Ohio, United States
University of Manitoba Health Sciences Centre
Winnipeg, Manitoba, Canada
Children's Hospital of Winnipeg
Winnipeg, Manitoba, Canada
Change in estimated glomerular filtration Rate (eGFR) from 6 months to 5 years post-transplantation
Modification of Diet in Renal Disease (MDRD) in the adult cohort and Schwartz method in the pediatric cohort
Time frame: Day 1
Patient survival as assessed by the incidence of death reported in the first 5 years post- transplant
Time frame: Day 1
Graft survival as assessed by the incidence of graft loss reported in the first 5 years post- transplant
Time frame: Day 1
Renal function as assessed by the absolute glomerular filtration Rate (GFR) at 5 years post-transplant
Time frame: Day 1
Change in Chronic Kidney Disease stages between transplant and 5 years post- transplant
Time frame: Day 1
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